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Cancer is a class of diseases or disorders characterized by uncontrolled division of cells and the ability of these cells to invade other tissues, either by direct growth into adjacent tissue through invasion or by implantation into distant sites by metastasis. Metastasis is defined as the stage in which cancer cells are transported through the bloodstream or lymphatic system. Cancer may affect people at all ages, but risk tends to increase with age, due to the fact that DNA damage becomes more apparent in aging DNA. It is one of the leading causes of death in developed countries.

There are a number of types of cancer. Severity of symptoms depends on the site and character of the malignancy and whether there is metastasis. A definitive diagnosis commonly requires the histologic examination of tissue by a pathologist. This tissue is obtained by biopsy or surgery. Most cancers can be treated and some cured, depending on the specific type, location, and stage. Once diagnosed, cancer is commonly treated with a combination of surgery, chemotherapy and radiotherapy. As research develops, therapys are becoming more specific for the type of cancer pathology. Drugs that target specific cancers already exist for several cancers. If untreated, cancers may eventually cause illness and death, though this is not always the case.

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A Cluster Bomb for Cancer Care

Chemotherapy, while an effective cancer therapy, also brings debilitating side effects such as nausea, liver toxicity and a battered immune system. Now, a new way to deliver this life-saving treatment to cancer patients - getting straight to the source of the disease - has been invented by Dr. Dan Peer of Tel Aviv University's Department of Cell Research and Immunology and the Center for Nano Science and Nano Technology together with Prof.........Go to the The-cancer-blog (Added on 8/24/2010 7:28:57 AM)

Assess severity of prostate cancers

Rutgers scientists are in the process of developing methods that can accurately assess the severity of prostate cancer by analyzing magnetic resonance images and spectra of a patient's prostate gland. This may help physicians decide more confidently which patients need aggressive therapy and which are better served by "watchful waiting," and could even postpone or eliminate invasive biopsies in patients with low-grade tumors. In a........Go to the The-cancer-blog (Added on 8/11/2010 7:07:46 AM)

Targeting advanced prostate cancer

In its early stages, prostate cancer requires androgens (hormones that promote the development and maintenance of male sex characteristics) for growth, and current first-line therapies target the receptor for these hormones to slow cancer's development and spread. However, advanced prostate cancers are often androgen-independent, meaning that androgen-blocking therapies are ineffective. Researchers aren't sure how this shift occurs as........Go to the The-cancer-blog (Added on 7/7/2010 7:00:50 AM)

Potential biomarkers for colorectal cancer

Colorectal cancer, cancer of the colon and rectum, is a common cause of mortality worldwide. Statistical data showed that the number of deaths caused by colorectal cancer is increasing in both men and women. Proteins are functional components of the cell that regulate the cell's activity. Understanding the differential expression of proteins in colorectal cancer and normal tissues will lead to a better understanding of the development of the........Go to the The-cancer-blog (Added on 6/24/2010 11:03:49 PM)

Key Enzyme in Melanoma Cell Development

Virginia Commonwealth University scientists have discovered a mechanism by which an enzyme regulates gene expression and growth in melanoma cells, a finding that could someday lead to more effective drugs to attack cancers and make them more treatable. Melanoma, the most serious type of skin cancer, is highly resistant to current therapeutic strategies for reasons that are not well understood. New research at VCU suggests that an enzyme........Go to the The-cancer-blog (Added on 6/18/2010 7:16:14 AM)

Exercise may keep cancer patients healthier

Breast and patients with prostate cancer who regularly exercise during and after cancer therapy report having a better quality of life and being less fatigued, as per scientists at Henry Ford Hospital in Detroit. "Using exercise as an approach to cancer care has the potential to benefit patients both physically and psychologically, as well as mitigate therapy side effects," says study main author Eleanor M. Walker, M.D., division director of........Go to the The-cancer-blog (Added on 5/21/2010 7:18:01 AM)

Gene can determine cancer susceptibility

It is an accepted fact that genetics play a key role in a person's susceptibility to cancer, and that throughout life, mutations can cause damage to tumor suppressor genes (TSGs) further increasing the chances of developing malignant tumors. Now a newly released study led by researchers at Beth Israel Deaconess Medical Center (BIDMC) demonstrates that even subtle changes in expression of the PTEN tumor suppressor gene can significantly........Go to the The-cancer-blog (Added on 4/24/2010 9:50:48 AM)

Cancer in the other breast in women with breast cancer

Postmenopausal women, including those over 70 years old, who have been newly diagnosed with cancer in one breast have higher cancer detection rates when the other breast is scanned for tumors with MRI, in comparison to premenopausal women, say scientists at the Mayo Clinic campus in Florida. They observed that 3.8 percent of 425 women had breast cancer in the undiagnosed breast that had not been found with a clinical or mammographic........Go to the The-cancer-blog (Added on 3/9/2010 8:35:18 AM)

A potent suppressor of endometrial cancer

Endometrial cancer is the most common cancer of the female reproductive tract, representing 6% of all cancers. There is currently no screening method or biomarker to indicate early presence of disease. "It is a very common malignancy that affects women of all ages" comments paper author Dr. Diego Castrillon. The cancer forms from the cells that grow along the inner lining of the uterus, which is called the endometrium, and commonly it is........Go to the The-cancer-blog (Added on 2/8/2010 7:43:40 AM)

Overcoming taxane resistance in cancer

Taxanes, a group of cancer drugs that includes paclitaxel (Taxol) and docetaxel (Taxotere), have become front-line treatment for a variety of metastatic cancers. But as with a number of chemotherapy agents, resistance can develop, a frequent problem in breast, ovarian, prostate and other cancers. Now, cancer scientists at Children's Hospital Boston report a protein previously unknown to be involved in taxane resistance and that could........Go to the The-cancer-blog (Added on 1/27/2010 8:22:46 AM)

Palliative care in health-care reform

New Rochelle, NY, January 15, 2010Opinion leaders in the field of palliative medicine explored the unparalleled opportunities that now exist for the palliative care community, which matches therapy to the desires of informed patients and their families, to help define evolving health care reform policy. The thought-provoking Roundtable discussion, "Palliative Medicine: Politics and Policy," is published online ahead of print in Journal of........Go to the The-cancer-blog (Added on 1/18/2010 8:17:25 AM)

New biomarkers for colon cancer

Researchers in China are reporting discovery of two proteins present in the blood, of people with colon cancer that may serve as the potential biomarkers for accurately predicting whether the disease will spread. Their study is in ACS' Journal of Proteome Research, a monthly publication. Maode Lai and his colleagues note that in 2008, 150,000 new cases of colon cancer and over 50,000 deaths from the disease occurred in the United States........Go to the The-cancer-blog (Added on 1/14/2010 8:18:53 AM)

The cancer 'TRAP'

Current research suggests that TNF-receptor associated protein-1 (TRAP-1) may prevent cancer cell death. The related report by Leav et al, "Cytoprotective Mitochondrial Chaperone TRAP-1 as a Novel Molecular Target in Localized and Metastatic Prostate Cancer," appears in the January 2010 issue of the American Journal of Pathology Prostate cancer is the most common type of cancer and is the second leading cause of cancer deaths among men in........Go to the The-cancer-blog (Added on 12/30/2009 8:03:17 AM)

Targets For Cancer And Degenerative Disease

Walter and Eliza Hall Institute researchers have identified a key step in the biological process of programmed cell death, also called apoptosis. Apoptosis is important in human biology as it removes unwanted and sometimes dangerous cells from our bodies, protecting us against cancer development. It can also, however, lead to the development of degenerative diseases when healthy cells are errantly destroyed. The research, led by Dr Ruth........Go to the The-cancer-blog (Added on 12/18/2009 7:14:31 PM)

Heart drugs show promise for fighting colon cancer

Researchers in Sweden are reporting for the first time that a group of drugs used to treat heart failure shows promise for fighting colon cancer. The study is in ACS' Journal of Natural Products, a monthly publication. Colon cancer is the third most common cancer in the United States, with more than 150,000 cases diagnosed in the U.S. each year. Jenny Felth, Joachim Gullbo, and his colleagues note that cardiac glycosides are a family of........Go to the The-cancer-blog (Added on 12/17/2009 8:13:07 AM)

Medical Scooters

Medical scooters, as the name suggests, are power-operated vehicles used as mobility aids for physically unfit people. These are also called electric scooters or mobility scooters and powered through batteries that are rechargeable. The seats on the two rear wheels may swivel for improved access. Medical Scooters: Types A mobility scooter comes in two main types, such as Front-wheel drive (FD): Ideal for indoor use, this scooter is........Go to the The-cancer-blog (Added on 12/15/2009 7:54:57 AM)

High-risk prostate cancer and bone mineral content loss

Men with prostate cancer lose significantly less bone mineral content (BMC) as they age than men who are free of the disease, as per research in the recent issue of BJUI The findings are important because loss of BMC can play a key role in the development of fragile bones, fractures and osteoporosis. American scientists studied 519 participants who joined the Baltimore Longitudinal Study at an average age of 56 between 1973 and 1984. The........Go to the The-cancer-blog (Added on 7/14/2010 7:48:42 AM)

Do spending cuts cost lives?

Radical cuts to social welfare spending to reduce budget deficits could cause not just economic pain but cost lives, warn experts as per a research findings published on bmj.com today. While there is a major debate under way about the potential economic impacts of radical budget cuts in Europe, David Stuckler from the University of Oxford and colleagues dissect the effect of public spending on people's health. Their analysis shows that........Go to the The-cancer-blog (Added on 6/24/2010 11:04:40 PM)

Studying Cells in 3-D

Showing movies in 3-D has produced a box-office bonanza in recent months. Could viewing cell behavior in three dimensions lead to important advances in cancer research? A newly released study led by Johns Hopkins University engineers indicates it may happen. Looking at cells in 3-D, the team members concluded, yields more accurate information that could help develop drugs to prevent cancer's spread. The study, a collaboration with scientists........Go to the The-cancer-blog (Added on 6/22/2010 7:20:38 AM)

Against advanced melanoma

The combination of two different chemotherapies and a previously approved therapy for kidney and liver cancers is not effective against advanced melanoma, as per results disclosed in an oral presentation today at the 46th annual meeting of the American Society of Clinical Oncology (ASCO) in Chicago. "With each newly released study, we learn something important about the therapy of melanoma," said John M. Kirkwood, M.D., professor of........Go to the The-cancer-blog (Added on 6/6/2010 8:45:41 PM)

Making the tumor glow

A series of novel imaging agents could light up tumors as they begin to form before they turn deadly and signal their transition to aggressive cancers. The compounds fluorescent inhibitors of the enzyme cyclooxygenase-2 (COX-2) could have broad applications for detecting tumors earlier, monitoring a tumor's transition from pre-malignancy to more aggressive growth, and defining tumor margins during surgical removal. "We're very excited........Go to the The-cancer-blog (Added on 4/29/2010 6:28:06 AM)

Getting Physical Against Cancer

Conventional biological wisdom holds that living cells interact with their environment through an elaborate network of chemical signals. As a result a number of therapies for the therapy of cancer and other diseases in which cell behavior goes awry focus on drugs that block or disrupt harmful chemical signals. Now, a new road for future therapies may have been opened with scientific evidence for a never seen before way in which cells can also........Go to the The-cancer-blog (Added on 3/11/2010 11:13:42 PM)

Gene mutation that causes endometrial cancer

A mutation in a single gene can cause endometrial cancer that is responsive to a specific drug treatment, scientists at UT Southwestern Medical Center have found in an animal study. The finding suggests that eventually it might be possible to screen women with endometrial cancer to see if they have that mutation and use the drug as targeted treatment, the scientists said. "Our data suggest that deficiency of this gene can indicate both........Go to the The-cancer-blog (Added on 2/10/2010 8:08:49 AM)

Cancer patients become bold advocates

Sociologists at Case Western Reserve University observed that when passive cancer patients become survivors, they have plenty of bold advice to offer other cancer patients, as per a research studyin JAGS, the Journal of American Geriatric Society Eva Kahana, Robson Professor of Sociology and director of the Elderly Care Research Center at Case Western Reserve, reported the findings from interviews with 100 cancer survivors. These survivors........Go to the The-cancer-blog (Added on 2/3/2010 8:21:01 AM)

Cancer studies with yeast

A researcher at Charles Drew University of Medicine and Science is investigating the potential use of non-pathogenic baker's yeast as a promising, natural treatment for cancer. Dr. Mamdooh Ghoneum presented his findings Tuesday, Feb. 2 at a special conference on "Cell Death Mechanism," sponsored by the American Association for Cancer Research (AACR) at the Omni San Diego Hotel in San Diego. "The central focus of the meeting is cell death........Go to the The-cancer-blog (Added on 2/3/2010 7:34:47 AM)

Frequency of surveillance colonoscopy

How often patients receive surveillance colonoscopy may need to be better aligned with their risks for colorectal cancer, as per two papers published this month by University of Pittsburgh School of Medicine researchers. The studies provide evidence that colonoscopy is both overused and underused in particular patient populations with serious implications for health care spending. As per Robert E. Schoen, M.D., M.P.H., professor of medicine........Go to the The-cancer-blog (Added on 1/14/2010 5:26:00 PM)

Therapy in oesophageal cancer

Cancer of the gullet, or oesophagus, is one of the ten most common cancers in the Western world, and there have been recent alarming increases in the number of cases each year in the US and UK. There is no good therapy, and sufferers frequently face a short, painful battle which ends all too quickly in death. A number of of the cancers diagnosed are in people with a long history of heartburn. Chronic heartburn leads to the lower parts of the........Go to the The-cancer-blog (Added on 1/12/2010 8:45:08 AM)

Celebrex prevents skin cancer

People with the heritable disorder of the skin called Gorlin syndrome who are genetically predisposed to develop basal cell carcinoma of the skin may have a new chemoprevention treatment on the horizon. As per results of a placebo-controlled, randomized, double-blind, Phase II study, the use of celecoxib was effective in inhibiting the development of basal cell carcinomas in a relatively rare group of patients who are highly susceptible to........Go to the The-cancer-blog (Added on 1/5/2010 8:43:22 AM)

BRCA1 gene and infertility

A New York Medical College doctor who specializes in restoring or preserving fertility in female cancer patients has discovered a possible link between the presence of breast cancer genes and infertility. In a paper published last week in the Journal of Clinical Oncology, Kutluk Oktay, M.D., professor of obstetrics and gynecology and principal investigator on the study, concluded that mutations in the BRCA1 gene, which have been linked with........Go to the The-cancer-blog (Added on 12/18/2009 6:30:25 PM)

Protecting cancer patients from H1N1 influenza

Despite a 100-fold increase in H1N1 influenza cases in the Seattle area during spring 2009, an aggressive infection control program to protect immunocompromised cancer patients and thorough screening measures resulted in no corresponding increase in H1N1 cases among the total patient population at the Seattle Cancer Care Alliance, as per a newly released study by scientists and physicians at Fred Hutchinson Cancer Research Center and the SCCA. ........Go to the The-cancer-blog (Added on 12/17/2009 8:02:55 AM)

Canada Drugs: Save a Bundle on Prescription Drugs

If you are looking to buy prescription drugs in Canada, online drug stores are the best place to visit. Certain benefits of purchasing drugs online include placing an order online to receive the shipment within about two weeks. Similarly, pharmacy search engines can help users locate the best companies to deal with. These search engines can also provide drug monographs, active ingredients and proprietary name. Customers can also compare drugs........Go to the The-cancer-blog (Added on 12/16/2009 11:18:35 PM)

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