http://www.thecancerblog.org/ New Article Alert From From Thecancerblog Wed, 14 May 2008 01:56:01 GMT en-us http://www.thecancerblog.org/images/blogs/thecancerblog.jpg http://www.thecancerblog.org/ 100 125 http://www.thecancerblog.org/blogs/permalinks/5-2008/chemical-compound-prevents-cancer-in-lab.html http://www.thecancerblog.org/blogs/permalinks/5-2008/chemical-compound-prevents-cancer-in-lab.html Wed, 14 May 2008 01:56:01 GMT While researching new ways to stop the progression of cancer, scientists at the University of Oklahoma Health Sciences Center, have discovered a compound that has shown to prevent cancer in the laboratory. The compound, which still faces several rounds of clinical trials, successfully stopped normal cells from turning into cancer cells and inhibited the ability of tumors to grow and form blood vessels. If proved to be successful tests continue, scientists eventually hope to create a daily pill that would be taken as a cancer preventive........ ]]> http://www.thecancerblog.org/blogs/permalinks/4-2008/destruct-triggers-may-be-jammed-in-tumor-cells.html http://www.thecancerblog.org/blogs/permalinks/4-2008/destruct-triggers-may-be-jammed-in-tumor-cells.html Wed, 14 May 2008 01:56:01 GMT Tumor cells living in the cross hairs of radiation or chemotherapy may be able to escape death because their self-destruct mechanisms are jammed, say University of Florida researchers writing in a recent issue of Developmental Cell. Researchers studying fruit fly cells discovered that slight changes in the protein scaffolds that support the genes reaper and hid aptly named for their roles in triggering cell death cause the cells to become naturally resistant to X-rays during early development........ ]]> http://www.thecancerblog.org/blogs/permalinks/4-2008/cells-on-the-road-to-cancer.html http://www.thecancerblog.org/blogs/permalinks/4-2008/cells-on-the-road-to-cancer.html Wed, 14 May 2008 01:56:01 GMT Using a common virus as a tool for investigating abnormal cell proliferation, a team led by researchers at Cold Spring Harbor Laboratory (CSHL) has succeeded in clarifying an intricate series of biochemical steps that shed light on a way that cancer can begin. The team's findings are the latest in a long and distinguished line of research at CSHL involving adenovirus, a type of virus that causes the common cold in people, but whose genome contains known oncogenes -- genes whose expression can promote cancer under certain conditions........ ]]> http://www.thecancerblog.org/blogs/permalinks/4-2008/obesity-inactivity-as-common.html http://www.thecancerblog.org/blogs/permalinks/4-2008/obesity-inactivity-as-common.html Wed, 14 May 2008 01:56:01 GMT EdmontonNew research supported by the Canadian Cancer Society shows that a number of cancer survivors in Canada are overweight and inactive, which could put them at risk for health problems, including their cancer returning. These findings tell us that we need to look at ways to better support cancer survivors to become more active and to maintain a healthy body weight, says Dr. Kerry Courneya, professor and Canada Research Chair at the University of Alberta in Edmonton, and affiliated scientist with the Centre for Behavioural Research and Program Evaluation. We know that physical inactivity and obesity are risk factors for developing cancer. These are also risk factors for the recurrence of cancer. Lifestyle is just as important after diagnosis........ ]]> http://www.thecancerblog.org/blogs/permalinks/4-2008/cancer-cells-spread-by-releasing-bubbles.html http://www.thecancerblog.org/blogs/permalinks/4-2008/cancer-cells-spread-by-releasing-bubbles.html Wed, 14 May 2008 01:56:01 GMT A new fundamental mechanism of how tumour cells communicate has just been discovered by the team of Dr. Janusz Rak at the Research Institute of the McGill University Health Centre (MUHC) in collaboration with Dr Guha from the University of Toronto. The cancer cells are able to communicate with their more healthy counter-parts by releasing vesicles. These bubble-like structures contain cancer-causing (oncogenic) proteins that can trigger specific mechanisms when they merge into non or less-cancerous cells. These findings could change our view on how malignant tissues work and lead to major clinical innovations. They were published on April 20 in the on-line edition of Nature Cell Biology........ ]]> http://www.thecancerblog.org/blogs/permalinks/4-2008/breakthrough-in-gene-therapy-for-cancer.html http://www.thecancerblog.org/blogs/permalinks/4-2008/breakthrough-in-gene-therapy-for-cancer.html Wed, 14 May 2008 01:56:01 GMT A revolutionary cancer therapy using microscopic magnets to enable 'armed' human cells to target tumours has been developed by scientists funded by the Biotechnology and Biological Sciences Research Council (BBSRC). Research published online today (17 April) in the journal, Gene Therapy, shows that inserting these nanomagnets into cells carrying genes to fight tumours, results in a number of more cells successfully reaching and invading cancerous tumours........ ]]> http://www.thecancerblog.org/blogs/permalinks/4-2008/vitamin-d-and-calcium-influence.html http://www.thecancerblog.org/blogs/permalinks/4-2008/vitamin-d-and-calcium-influence.html Wed, 14 May 2008 01:56:01 GMT Scientists at Emory University are learning how vitamins and minerals in the diet can stimulate or prevent the appearance of colon cancer. Emory researchers will present their findings on biological markers that could influence colon cancer risk in three abstracts at the American Association for Cancer Research meeting in San Diego........ ]]> http://www.thecancerblog.org/blogs/permalinks/4-2008/a-better-mouse-model-for-cancer-research.html http://www.thecancerblog.org/blogs/permalinks/4-2008/a-better-mouse-model-for-cancer-research.html Wed, 14 May 2008 01:56:01 GMT Scientists at Boston College have developed the first laboratory mouse model that mimics cancers spread through the human body. Using their novel cell line, the team discovered one of the bodys primary defensive cells plays a role in cancers attack. The development of a new animal model a line of cancer cells injected into a laboratory mouse that displays the full spectrum of systemic metastatic cancer in humans removes a "scientific stumbling block" in advancing cancer research and potential therapys, as per Boston College Biologist Thomas Seyfried, whose findings appear this week in the online version of the International Journal of Cancer and will be presented at the annual meeting of the American Association of Cancer Research in San Diego........ ]]> http://www.thecancerblog.org/blogs/permalinks/4-2008/double-binding-sites-on-tumor-target.html http://www.thecancerblog.org/blogs/permalinks/4-2008/double-binding-sites-on-tumor-target.html Wed, 14 May 2008 01:56:01 GMT Scientists from the University of Pennsylvania School of Medicine and his colleagues at Merck Serono Research in Gera number of have observed that two drugs bind to receptor sites on some tumors in different places at the same time, suggesting the possibility of a new combination treatment for certain types of cancer........ ]]> http://www.thecancerblog.org/blogs/permalinks/3-2008/anti-cancer-drugs-and-new-de-methylating-agents.html http://www.thecancerblog.org/blogs/permalinks/3-2008/anti-cancer-drugs-and-new-de-methylating-agents.html Wed, 14 May 2008 01:56:01 GMT Scientists at the National Sun Yat-Sen University and Kaohsiung Medical University, Kaohsiung, Taiwan have revealed a new mechanism by which nonsteroidal anti-inflammatory drugs (NSAIDs) attenuate tumor invasion and metastasis. The research, would be reported in the April 2008 issue of Experimental Biology and Medicine, provides new insights for the understanding of the anti-cancer effects of NSAIDs........ ]]> http://www.thecancerblog.org/blogs/permalinks/3-2008/halting-the-growth-of-a-childhood-brain-cancer.html http://www.thecancerblog.org/blogs/permalinks/3-2008/halting-the-growth-of-a-childhood-brain-cancer.html Wed, 14 May 2008 01:56:01 GMT A discovery by St. Jude Childrens Research Hospital researchers suggests a safer way to treat medulloblastoma, a rare but often fatal childhood brain tumor. The group observed that one of the brains signaling pathways inhibits the growth of the highly aggressive cancer cells. The scientists discovered that three proteins, designated BMP2, BMP4 and BMP7, halted the growth of medulloblastoma tumors and induced the cancerous cells to develop into normal neurons........ ]]> http://www.thecancerblog.org/blogs/permalinks/3-2008/allergic-reaction-to-cancer-drug.html http://www.thecancerblog.org/blogs/permalinks/3-2008/allergic-reaction-to-cancer-drug.html Wed, 14 May 2008 01:56:01 GMT Clinicians have been perplexed by the fact that some patients given the drug cetuximaban immune-based treatment usually used to treat persons diagnosed with head and neck cancer, or colon cancerhave a severe and rapid adverse reaction to the drug. Sometimes the reaction includes anaphylaxis, a life-threatening condition characterized by a drop in blood pressure, fainting, difficulty breathing, and wheezing. Now scientists funded by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, have discovered that specific pre-existing antibodies cause the severe reaction to the drug. This discovery in turn has enabled them to explain the unusual geographic pattern of this reaction seen among individuals in the United States. The unusual findings of this investigation appear in a report reported in the March 13 edition of the New England Journal (NEJM)........ ]]> http://www.thecancerblog.org/blogs/permalinks/3-2008/fugitive-cancer-cells-can-be-blocked.html http://www.thecancerblog.org/blogs/permalinks/3-2008/fugitive-cancer-cells-can-be-blocked.html Wed, 14 May 2008 01:56:01 GMT Cancer cells get a helping hand from platelets, specialized blood cells involved in clotting. Platelets shelter and feed tumor cells that stray into the bloodstream, making it easier for cancer to spread, or metastasize. Research at Washington University School of Medicine in St. Louis suggests that inactivating platelets could slow down or prevent metastasis........ ]]> http://www.thecancerblog.org/blogs/permalinks/3-2008/updated-colorectal-cancer-screening-guidelines.html http://www.thecancerblog.org/blogs/permalinks/3-2008/updated-colorectal-cancer-screening-guidelines.html Wed, 14 May 2008 01:56:01 GMT The American Cancer Society, the American College of Radiology, and the U.S. Multi-Society Task Force on Colorectal Cancer (a group that comprises representatives from the American College of Gastroenterology, American Gastroenterological Association, and American Society for Gastrointestinal Endoscopy) have released the first-ever joint consensus guidelines for colorectal cancer screening. The guidelines add two new tests to the list of recommended options: stool DNA (sDNA) and CT colonography (CTC), also known as virtual colonoscopy, and for the first time include a preference for screening tests that can not only detect cancer early but also detect premalignant polyps, as those tests provide a greater potential for cancer prevention through polyp removal........ ]]> http://www.thecancerblog.org/blogs/permalinks/3-2008/head-and-neck-cancer-patients.html http://www.thecancerblog.org/blogs/permalinks/3-2008/head-and-neck-cancer-patients.html Wed, 14 May 2008 01:56:01 GMT Using a combination of positron emission tomography (PET) and computed tomography for radiation treatment therapy planning in head and neck carcinoma patients provides for excellent, local and regional disease control when in comparison to CT alone, as per a research studyin the March 1 issue of the International Journal for Radiation Oncology*Biology*Physics, the official journal of the American Society for Therapeutic Radiology and Oncology........ ]]>