Molecular imaging technology for gastric cancerModern cancer care is critically dependent on imaging technologies, which are used to detect early tumors and guide their therapy or surgery. Molecular imaging technologies provide information about the functional or metabolic characteristics of malignancies, tumor stage and therapeutical response, and tumor recurrence; whereas conventional imaging technologies predominantly assess the tumor's anatomical or morphologic features including its........Go to the The-cancer-blog (Added on 9/24/2008 6:17:50 PM)
As head and neck cancer risks evolveAdvances in understanding head and neck cancer over the last decade have led to more therapy options and improved quality of life for patients, as per a review published this week in the New England Journal (NEJM)
The authors are Dong M. Shin, MD, Frances Kelly Blomeyer Distinguished Professor and associate director of Emory University School of Medicines Winship Cancer Institute, and Robert Haddad, MD, assistant professor of medicine at........Go to the The-cancer-blog (Added on 9/10/2008 7:31:17 PM)
Adult survivors of childhood cancer smokeOne-fifth of British adult survivors of childhood cancers are current smokers, and nearly a third have been regular smokers at some point in their lives, as per a research studyin the July 29 online issue of the Journal of the National Cancer Institute
Adult survivors of childhood cancer are at increased risk of developing cardiovascular disease, lung problems, and second malignancies, relative to the general public. These increased risks........Go to the The-cancer-blog (Added on 7/30/2008 12:11:16 AM)
Predicting outcomes for stomach cancer patientsScientists at Rhode Island Hospital have identified two potential molecular markers that may predict outcomes for patients with stomach cancer, one of the most common and fatal cancers worldwide.
As per the study, reported in the July 1 issue of Clinical Cancer Research, patients who had poor outcomes following surgery for stomach cancer also had extremely low amounts of two proteins, known as gastrokine 1 and 2 (GKN1 and GKN2), which are........Go to the The-cancer-blog (Added on 7/16/2008 8:30:23 PM)
Cancer preventive properties of ResveratrolEarly laboratory research has shown that resveratrol, a common dietary supplement, suppresses the abnormal cell formation that leads to most types of breast cancer, suggesting a potential role for the agent in breast cancer prevention.
Resveratrol is a natural substance found in red wine and red grapes. It is sold in extract form as a dietary supplement at most major drug stores.
"Resveratrol has the ability to prevent the first step that........Go to the The-cancer-blog (Added on 7/7/2008 9:53:50 PM)
Designer diet for prostate cancerEating one or more portions of broccoli every week can reduce the risk of prostate cancer, and the risk of localised cancer becoming more aggressive.
For the first time, a research group at the Institute of Food Research led by Professor Richard Mithen has provided an explanation of how eating broccoli might reduce cancer risk based upon studies in men, as opposed to trying to extrapolate from animal models. Prostate cancer is the most........Go to the The-cancer-blog (Added on 7/1/2008 8:38:37 PM)
'Addicted' cells provide early cancer diagnosisResearchers at the Institute of Food Research have detected subtle changes that may make the bowel more vulnerable to the development of tumours.
With support from the Food Standards Agency and the Biotechnology and Biological Sciences Research Council they are investigating whether diet could control these changes and delay or reverse the onset of cancer.
"We looked at changes in 18 genes that play a role in the very earliest stages of........Go to the The-cancer-blog (Added on 6/10/2008 10:19:08 PM)
Patients 75 years and older with brain tumorsA new study from University Hospitals Case Medical Center (UHCMC) finds that elderly patients 75 years old and older-- with cancerous brain tumors are not treated as aggressively as patients between 65 and 75 years old. Furthermore, the scientists find that if patients over 75 years old are treated aggressively, such as with surgery and radiation, they have better survival rates. The findings are reported in the recent issue of the Journal of........Go to the Cancer-articles (Added on 5/19/2008 6:38:11 PM)
Chemical Compound Prevents Cancer In LabWhile researching new ways to stop the progression of cancer, scientists at the University of Oklahoma Health Sciences Center, have discovered a compound that has shown to prevent cancer in the laboratory.
The compound, which still faces several rounds of clinical trials, successfully stopped normal cells from turning into cancer cells and inhibited the ability of tumors to grow and form blood vessels. If proved to be successful tests........Go to the The-cancer-blog (Added on 5/13/2008 7:56:01 PM)
'Destruct' triggers may be jammed in tumor cellsTumor cells living in the cross hairs of radiation or chemotherapy may be able to escape death because their self-destruct mechanisms are jammed, say University of Florida researchers writing in a recent issue of Developmental Cell.
Researchers studying fruit fly cells discovered that slight changes in the protein scaffolds that support the genes reaper and hid aptly named for their roles in triggering cell death cause the cells to become........Go to the The-cancer-blog (Added on 4/30/2008 6:06:49 PM)
Obesity, inactivity as common among cancer survivorsEdmontonNew research supported by the Canadian Cancer Society shows that a number of cancer survivors in Canada are overweight and inactive, which could put them at risk for health problems, including their cancer returning.
These findings tell us that we need to look at ways to better support cancer survivors to become more active and to maintain a healthy body weight, says Dr. Kerry Courneya, professor and Canada Research Chair at the........Go to the The-cancer-blog (Added on 4/21/2008 9:11:31 PM)
Vitamin D and calcium influence cell death in the colonScientists at Emory University are learning how vitamins and minerals in the diet can stimulate or prevent the appearance of colon cancer.
Emory researchers will present their findings on biological markers that could influence colon cancer risk in three abstracts at the American Association for Cancer Research meeting in San Diego.
In a clinical study of 92 patients, supplementing diet with calcium and vitamin D appeared to increase the........Go to the The-cancer-blog (Added on 4/13/2008 8:58:06 PM)
A better mouse model for cancer researchScientists at Boston College have developed the first laboratory mouse model that mimics cancers spread through the human body. Using their novel cell line, the team discovered one of the bodys primary defensive cells plays a role in cancers attack.
The development of a new animal model a line of cancer cells injected into a laboratory mouse that displays the full spectrum of systemic metastatic cancer in humans removes a "scientific........Go to the The-cancer-blog (Added on 4/9/2008 9:49:04 PM)
Anti-cancer drugs and new de-methylating agentsScientists at the National Sun Yat-Sen University and Kaohsiung Medical University, Kaohsiung, Taiwan have revealed a new mechanism by which nonsteroidal anti-inflammatory drugs (NSAIDs) attenuate tumor invasion and metastasis. The research, would be reported in the April 2008 issue of Experimental Biology and Medicine, provides new insights for the understanding of the anti-cancer effects of NSAIDs.
NSAIDs have been used for the suppression........Go to the The-cancer-blog (Added on 3/26/2008 9:53:33 PM)
Cause of severe allergic reaction to cancer drugClinicians have been perplexed by the fact that some patients given the drug cetuximaban immune-based treatment usually used to treat persons diagnosed with head and neck cancer, or colon cancerhave a severe and rapid adverse reaction to the drug. Sometimes the reaction includes anaphylaxis, a life-threatening condition characterized by a drop in blood pressure, fainting, difficulty breathing, and wheezing. Now scientists funded by the National........Go to the The-cancer-blog (Added on 3/12/2008 9:43:44 PM)
Updated colorectal cancer screening guidelinesThe American Cancer Society, the American College of Radiology, and the U.S. Multi-Society Task Force on Colorectal Cancer (a group that comprises representatives from the American College of Gastroenterology, American Gastroenterological Association, and American Society for Gastrointestinal Endoscopy) have released the first-ever joint consensus guidelines for colorectal cancer screening. The guidelines add two new tests to the list of........Go to the The-cancer-blog (Added on 3/5/2008 8:56:24 PM)
The cancer-related protein AktThe cancer-related protein Akt may profoundly influence the fate of the tau protein, which forms bundles of tangled nerve cell fibers in the brain linked to Alzheimer's disease, reports a new study led by scientists at the University of South Florida and the Mayo Clinic in Jacksonville, FL.
The study was published online Feb. 21 in the Proceedings of the National Academy of Sciences of the United States of America.
The findings may........Go to the Cancer-articles (Added on 2/28/2008 10:20:18 PM)
Chemo holidays for men with advanced prostate cancerThe double-blind, randomized study, led by principal investigator Tomasz Beer, M.D., recently was reported in the journal Cancer. Beer is the Grover C. Bagby Endowed Chair for Cancer Research, director of the OHSU Cancer Institute Prostate Cancer Program, and associate professor of medicine (hematology/medical oncology), OHSU School of Medicine.
Beer and his team wanted to know if men with metastatic, androgen-independent prostate cancer ........Go to the The-cancer-blog (Added on 2/25/2008 9:26:39 PM)
Single reader with CAD more efficientSingle reading of screening mammograms with computer-aided detection (CAD) is more efficient than double reading and yields a higher sensitivity than the first reader in a double reading program, according to a study conducted by researchers at Charlotte Radiology in Charlotte, NC. In addition, the readings with CAD had a significantly lower recall rate than double reading.
The double reading method consisted of the mammogram being first........Go to the The-cancer-blog (Added on 2/14/2008 10:22:38 PM)
Fruit flies all aglow light the way to cancer preventionA green glow from a fruit fly is giving scientists the green light when they are on the right path in their quest to develop compounds that help prevent cancer.
The glow, the result of some tinkering in Drosophila, the workhorse of the genetics world, lets scientists know when powerful cancer-prevention signals similar to those spurred by protective chemicals in broccoli, cabbage, and other foods, have been turned on in the organism.
The........Go to the The-cancer-blog (Added on 1/14/2008 5:21:11 PM)
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Proton therapy lowers chance of later cancersBoston Patients who are treated with proton treatment (a specialized type of external beam radiation treatment using protons rather than X-rays to treat cancer) decreases the risk of patients developing a secondary cancer by two hundred percent, in comparison to being treated with standard photon radiation therapy, as per a first-of-its-kind study presented September 22, 2008, at the American Society for Therapeutic Radiology and Oncology's........Go to the The-cancer-blog (Added on 9/22/2008 10:35:38 PM)
New tool to speed cancer therapy approval availableEventhough cancer remains a leading cause of death in America, it can take up to 12 years to bring a new anti-cancer agent before the FDA and the success rate for approval is only five to 10 percent. That means a number of research hours and dollars are wasted chasing avenues that will not bring fruit.
The National Cancer Institute's Translational Research Working Group (TRWG) developed a set of tools that it believes will improve that........Go to the Cancer-articles (Added on 9/15/2008 10:07:08 PM)
Clon cancer and gatekeeper geneThe absence or inactivation of the RUNX3 gatekeeper gene paves the way for the growth and development of colon cancer, Singapore researchers report in the Sept. issue of the journal Cancer Cell Prior studies have shown that RUNX3 plays a role in gastric, breast, lung and bladder cancers.
The inactivation of RUNX3 occurs at a very early stage of colon cancer, as per the Singapore scientists' studies with human tissue samples and animal........Go to the The-cancer-blog (Added on 9/9/2008 9:40:24 PM)
Mechanism that regulates cell movementA study performed by scientists at the Institute for Research in Biomedicine (IRB Barcelona), in collaboration with scientists at the Instituto de Biologa Molecular of the CSIC, reveal a mechanism that controls the movement of cells in a tissue by regulating cell adhesion. This same mechanism may be defective in diseases such as cancer and its metastasis, when tumour cells lose their adhesion to neighbouring cells and migrate through the........Go to the The-cancer-blog (Added on 7/20/2008 2:30:12 PM)
Cancer cells revert to normal at specific signal thresholdCancer starts when key cellular signals run amok, driving uncontrolled cell growth. But researchers at the Stanford University School of Medicine report that lowering levels of one cancer signal under a specific threshold reverses this process in mice, returning tumor cells to their normal, healthy state. The finding could help target cancer chemotherapy to tumors while minimizing side effects for the body's healthy cells.
The scientists........Go to the The-cancer-blog (Added on 7/1/2008 9:43:05 PM)
Pinpointing Prostate Cancer RecurrenceA simple blood test may help doctors better predict whether prostate cancer will recur or spread in patients who have undergone surgery for the disease, UT Southwestern Medical Center scientists have found.
As per a research findings reported in the June 15 issue of Clinical Cancer Research, UT Southwestern researchers identified a panel of seven biomarkers that can predict with 86 percent accuracy which patients with prostate cancer will........Go to the The-cancer-blog (Added on 6/17/2008 9:48:27 PM)
Stabilizing cancer-fighting p53HOUSTON - Efforts to protect the tumor-suppressor p53 could just as easily shelter a mutant version of the protein, causing cancer cells to thrive and spread rather than die, as per research by researchers at The University of Texas M. D. Anderson Cancer Center published in the current issue of the journal Genes and Development.
"As we develop therapies to restore the function of p53, we need to make sure we first know what version of this........Go to the The-cancer-blog (Added on 5/22/2008 10:28:46 PM)
OHSU Discovery May Lead to Early Cancer DetectionOHSU pancreas cancer expert Brett Sheppard, M.D., and his colleagues in the OHSU Oregon Stem Cell Center, have developed antibodies that recognize pancreas cancer; Sheppard is presenting these findings this week during Digestive Disease Week in San Diego.
This week scientists in the Oregon Health & Science University (OHSU) Oregon Stem Cell Center and the OHSU Digestive Health Center are shining a new ray of hope on patients with pancreas........Go to the The-cancer-blog (Added on 5/22/2008 10:14:31 PM)
M. D. Anderson nurse addresses lymphedemaA poster session presented today by The University of Texas M. D. Anderson Cancer Center at the Oncology Nurses Society 33rd Annual Congress, observed that early nursing intervention and implementation of effective strategies can lead to a decrease in the occurence rate of lymphedema, better management of chronic lymphedema and improved quality of life in patients with breast cancer.
The literature review, led by Mattie J. Sennett McDowell,........Go to the The-cancer-blog (Added on 5/18/2008 9:42:45 PM)
Cells on the Road to CancerUsing a common virus as a tool for investigating abnormal cell proliferation, a team led by researchers at Cold Spring Harbor Laboratory (CSHL) has succeeded in clarifying an intricate series of biochemical steps that shed light on a way that cancer can begin.
The team's findings are the latest in a long and distinguished line of research at CSHL involving adenovirus, a type of virus that causes the common cold in people, but whose genome........Go to the The-cancer-blog (Added on 4/22/2008 9:05:12 PM)
Cancer cells spread by releasing 'bubbles' A new fundamental mechanism of how tumour cells communicate has just been discovered by the team of Dr. Janusz Rak at the Research Institute of the McGill University Health Centre (MUHC) in collaboration with Dr Guha from the University of Toronto.
The cancer cells are able to communicate with their more healthy counter-parts by releasing vesicles. These bubble-like structures contain cancer-causing (oncogenic) proteins that can trigger........Go to the The-cancer-blog (Added on 4/21/2008 8:15:48 PM)
Tiny magnets offer breakthrough in gene therapy for cancerA revolutionary cancer therapy using microscopic magnets to enable 'armed' human cells to target tumours has been developed by scientists funded by the Biotechnology and Biological Sciences Research Council (BBSRC). Research published online today (17 April) in the journal, Gene Therapy, shows that inserting these nanomagnets into cells carrying genes to fight tumours, results in a number of more cells successfully reaching and invading........Go to the The-cancer-blog (Added on 4/17/2008 8:25:05 PM)
Double binding sites on tumor targetScientists from the University of Pennsylvania School of Medicine and his colleagues at Merck Serono Research in Gera number of have observed that two drugs bind to receptor sites on some tumors in different places at the same time, suggesting the possibility of a new combination treatment for certain types of cancer.
An increasing number of therapies targeting tumors that have proteins called epidermal growth factor receptors (EGFR) sitting........Go to the The-cancer-blog (Added on 4/8/2008 10:24:19 PM)
Halting the growth of a childhood brain cancerA discovery by St. Jude Childrens Research Hospital researchers suggests a safer way to treat medulloblastoma, a rare but often fatal childhood brain tumor. The group observed that one of the brains signaling pathways inhibits the growth of the highly aggressive cancer cells.
The scientists discovered that three proteins, designated BMP2, BMP4 and BMP7, halted the growth of medulloblastoma tumors and induced the cancerous cells to develop........Go to the The-cancer-blog (Added on 3/16/2008 9:29:28 PM)
Fugitive cancer cells can be blockedCancer cells get a helping hand from platelets, specialized blood cells involved in clotting. Platelets shelter and feed tumor cells that stray into the bloodstream, making it easier for cancer to spread, or metastasize. Research at Washington University School of Medicine in St. Louis suggests that inactivating platelets could slow down or prevent metastasis.
In advance online publication in the Journal of Cellular Biochemistry, the........Go to the The-cancer-blog (Added on 3/9/2008 6:06:26 PM)
PET/CT planning beneficial for head and neck cancer patientsUsing a combination of positron emission tomography (PET) and computed tomography for radiation treatment therapy planning in head and neck carcinoma patients provides for excellent, local and regional disease control when in comparison to CT alone, as per a research studyin the March 1 issue of the International Journal for Radiation Oncology*Biology*Physics, the official journal of the American Society for Therapeutic Radiology and Oncology.
........Go to the The-cancer-blog (Added on 3/4/2008 5:38:20 PM)
Arsenic aids tumor imagingArsenic associated with a drug that binds to the blood vessels of malignant tumors provides a powerful imaging agent that could one day allow physicians to detect hard-to-find tumors and more closely monitor cancers response to treatment, scientists at UT Southwestern Medical Center have found.
The findings, based on animal studies and appearing in todays issue of Clinical Cancer Research, mark the first time arsenic has been used to label........Go to the The-cancer-blog (Added on 3/2/2008 8:41:16 PM)
Cell phone-cancer link foundAn Israeli scientist, Dr. Siegal Sadetzki, has found a link between cell phone usage and the development of tumors.
Dr. Sadetzki, a physician, epidemiologist and lecturer at Tel Aviv University, published the results of a study recently in the American Journal of Epidemiology, in which she and her colleagues observed that heavy cell phone users were subject to a higher risk of non-malignant and cancerous tumors of the salivary gland.
........Go to the Cancer-articles (Added on 2/14/2008 10:27:44 PM)
Gene Play Role in Skin Cancer DevelopmentScientists at the Burnham Institute for Medical Research (Burnham Institute) have provided genetic evidence that Activating Transcription Factor 2 (ATF2) plays a suppressor role in skin cancer development. ATF2 is a protein that regulates gene transcription, which is the first step in the translation of genetic code, in response to extracellular stresses such as ultraviolet light and ionizing radiation. This function of ATF2 in stress and DNA........Go to the The-cancer-blog (Added on 2/6/2008 8:18:11 PM)
4 health behaviors can add 14 extra years of lifePeople who adopt four healthy behaviours not smoking; taking exercise; moderate alcohol intake; and eating five servings of fruit and vegetables a day live on average an additional fourteen years of life compared with people who adopt none of these behaviours, according to a study published in the open access journal PLoS Medicine.
Rather than focusing on how an individual factor is related to health, the study calculates the combined........Go to the Cancer-articles (Added on 1/8/2008 5:20:32 AM)
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